ericjelli02 - Network

Today I tried out #AMD #Instinct #MI300a for my existing Deep Learning pipeline. Good news: It worked out of the box. Bad news: For some...

Today I tried out #AMD #Instinct #MI300a for my existing Deep Learning pipeline. Good news: It worked out of the box. Bad news: For some reason it could not beat my local #Nvidia #1080ti...
After trying all sorts of #ROCM installation methods via prebuild wheels, #apptainer images etc I tried #nanogpt by @karpathy and sure enought: The gpt code ran approx 2x faster than on a #a100 ... I hope that this is due to my programming skills. Not AMD prefering #transformers over #CNNs ...

Wer kennt es nicht: #Literaturrecherche ist mühsam ... Relevante Artikel in #googlescholar finden, Benachrichtigung einstellen sobald...

Wer kennt es nicht: #Literaturrecherche ist mühsam ... Relevante Artikel in #googlescholar finden, Benachrichtigung einstellen sobald dieser zitiert wird, und hoffen dass das Postfach nicht überrannt wird ...
Es wird Zeit #OpenAlex ausprobieren: Auf den ersten Blick hat es wesentlich mehr Filtermöglichkeiten für Benachrichtigungen. Im Gegensatz zu #Google handelt es sich um eine Nonprofit die alle Daten auch per #API offen zur Verfügung stellt...

https://openalex.org/

#TIL that you can verify the #ssh #hostkeys of a on-premise-hosted #gitlab by going to <gitlab-url>/help/instance_configuration...

#TIL that you can verify the #ssh #hostkeys of a on-premise-hosted #gitlab by going to <gitlab-url>/help/instance_configuration 🎉

I.e. for the #gwdg instance you can visit https://gitlab.gwdg.de/help/instance_configuration

As already indicated by previous experiments, not only #V_cholerae reacts to purified #peptidoglycan but this behaviour can also be observed...

As already indicated by previous experiments, not only #V_cholerae reacts to purified #peptidoglycan but this behaviour can also be observed in different biofilm-forming species.

So Sanika has "demonstrated that exogenous PG released by cellular lysis is a general danger signal to which several bacterial species respond by forming biofilms. The resulting biofilms serves as a refuge that protects against phage predation or other biotic and abiotic stresses that can lyse bacterial cells."

Still, the signal was missing ... and the signal hunt was on ... and escalated quickly. While some experiments with differently threated...

Still, the signal was missing ... and the signal hunt was on ... and escalated quickly. While some experiments with differently threated lysates showed that biofilm-inducing molecules had a wide range of sizes, but they have to be larger than 3 kDa. Others pointed into the direction of exogenously cell wall fragments. Indeed, the exposure of #V_cholerae to purified #peptidoglycan triggered the biofilm formation!

After exploring different hypotheses, a control experiment revealed that not only #lysate of #V_cholerae communities but also from #E_coli,...

After exploring different hypotheses, a control experiment revealed that not only #lysate of #V_cholerae communities but also from #E_coli, #P_aeruginosa, and even #Gram-negative bacteria such as #B_subtilis can trigger the response.

While biofilm formation of bacterial species as a stress response is not really something unheard of, the reconstruction of the exact signal...

While biofilm formation of bacterial species as a stress response is not really something unheard of, the reconstruction of the exact signal pathway came with a surprise: It is not necessary that the bacterial cells are exposed to phages at all but rather sufficient to expose them to the left-overs of a previous phage attack.

During her research at the #mpitm, Sanika found that #V_cholerae forms biofilms directly after treated with #phages.

During her research at the #mpitm, Sanika found that #V_cholerae forms biofilms directly after treated with #phages.

Nice work by Sanika Vaidya (and collegues)done during our PhDs together at @maxplanckgesellschaft and @unibaselPeptidoglycan triggers...

Nice work by Sanika Vaidya (and collegues)
done during our PhDs together at @maxplanckgesellschaft and @unibasel

Peptidoglycan triggers #biofilm formation across bacterial species.

https://www.nature.com/articles/s41564-024-01886-5

#openaccess #mpg #mpitm #phage #V_cholerae #bacteria #nature #microbiology #science #research

#instanceMove Since social.mpdl.mpg.de will be closed at the end of 2024, I will move my account @jeller to academiccloud.social.

#instanceMove Since social.mpdl.mpg.de will be closed at the end of 2024, I will move my account @jeller to academiccloud.social.